Research Senior Associate, Oncology Cell Therapy

Job title: Research Senior Associate, Oncology Cell Therapy in Boston, MA at Takeda

Company: Takeda

Job description: By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s and . I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionPursuant to Section 20 C.F.R. 656.10, you are hereby notified that an application for Alien Employment Certification will be filed by Takeda Development Center Americas, Inc. for the following job opportunity:JOB LOCATION: Cambridge, MAPOSITION: Research Senior Associate, Oncology Cell TherapyPOSITION DESCRIPTION: Takeda Development Center Americas, Inc. is seeking a Research Senior Associate, Oncology Cell Therapy with the following duties: maintain primary immune cell cultures and produce human and mouse CAR T cells. Plan, prioritize, and execute CAR gamma-delta T cell production, applying leadership qualities to facilitate a seamless workflow for experiments. Establish new experimental designs for CAR T cells co-cultured with differentially activated fibroblasts and other target cell types using a range of techniques and analytical method such as ELISA/MSD, flow cytometry, cytotoxicity readouts, and/or gene expression. Produce, titer, and bank viral vectors to express CAR and other constructs in T cells. Collaborate with project representatives to plan experiments, analyze and interpret data, and communicate findings internally. Prepare study protocols, reports, and documentation. Work with manager and teammates to troubleshoot complex problems in creative and effective ways. Actively participate in the innovation and optimization of cell therapy processes to ensure the delivery of project goals. Up to 20% remote work allowed.REQUIREMENTS: Master’s degree in Biotechnology or related field, plus 1 year of related experience. Prior experience must include: maintain primary cell cultures, process tissue samples into single cell suspensions, cryopreserve and recover cell lines and primary immune cells; execute protein and cell binding assays including ELISA and viral vector titration; perform flow cytometry-based experiments, including panel optimization, gating strategy, and data analysis; serve as an internal expert for BD Symphony and Aria Fusion flow cytometers, including maintenance and troubleshooting, consulting to optimize instrument setup, and assisting users to operate the instruments; optimize organoid-based assays through collaboration and establish in-vitro assays for allergy research; lead and collaborate to develop and optimize a Standard Operating Protocol for bulk RNA sequencing.Full time. $86,500 to $148,300 per year. Competitive compensation and benefits.Qualified applicants can apply at . Please reference job # R0152593. EOEAny individual may provide documentary evidence bearing on this application, with information on available workers and information on wages and working conditions, to the Certifying Officer, U.S. Department of Labor, Employment and Training Administration, Office of Foreign Labor Certification, 200 Constitution Avenue, NW, Room N-5311, Washington, DC 20210.Locations Boston, MAWorker Type EmployeeWorker Sub-Type RegularTime Type Full time

Expected salary: $86500 - 148300 per year

Location: Boston, MA

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